Title: Potential role for growth hormone in human lactation insufficiency

标题：生长激素对人母泌乳不足的潜在作用

Content/内容：

1) In order to evaluate the galactopoietic response to rhGH in mothers of normal babies with idiopathic lactation insufficiency arising in the early postpartum period, we performed a preliminary, randomised, single blind trial of 3 different doses of hGH: either 0.05, 0.1, ог 0.2 IU/kg/day to a maximum of 16 IU/day, for 7 days.

为了评价生长激紧对婴儿正常人母在产后非特异性泌乳不足的催乳反应，作者进行随机单盲预试验，给受试者分别注射3种不同剂量的人生长激素：0.05、0.01、0.02 IU/kg/d，然后增至最大剂量16 IU/d，连续7天。

2) Total 24-hour milk production was determined in each mother 1 day prior to initiating therapy and on the last day of therapy.

每位产妇在治疗前与治疗结束日测定24小时总泌乳量。

3) Milk production rose by 36.0±12.6% in the group receiving 0.2 IU/kg/day (n=6) but by only 4.7±9.7%, (P<0.04) in the combined lower dose group (n=10).

接受0.2 IU/kg/d(n=6)者的泌乳量增加 36.0±12.6%(P<0.04)，但综合低剂量组(n=10)仅增加4.7士9.7%。

4) In conclusion, these data suggest that moderate dose hGH therapy in mothers with lactation insufficiency can improve galactopoiesis.

总之，这些数据表明，中等剂量的hGH疗法可改善泌乳不足产妇的乳生成。

责任编辑：admin