Title: Sudden death in hypertrophic myocardiopathy
标题：肥厚性心肌病性猝死
Content/内容：
1) Hypertrophic cardiomyopathy is the most common cause of sudden death in young individuals who are otherwise healthy.
肥厚性心肌病是无其他疾患的青年人中最常见的猝死原因。
2) Risk of sudden death is highest in patients who are between 14 and 35 years old.
14~35岁患者的猝死危险度最高。
3) Several mechanisms are involved in sudden death: ventricular arrhythmias, supraventricular arrhythmias leading to cardiac collapse. bradycardias and severe ischemia.
猝死涉及以下机制：室性心律失常、室上性心律失常导致心源性休克、心动过缓及重度心肌缺血。
4) The factors that best identify high risk patients are: previous history of sudden death or syncope, induction in adults of sustained ventricular arrhythmias, the presence of non-sustained ventricular tachycardia in symptomatic patients, the presence of ischemia associated with hypotension in children, the presence of mutations in the beta-myosin heavy chain together with a family history of sudden death and a poor left ventricular ejection fraction.
有助于识别高危病人的最佳因素有猝死或晕厥过去病史、成人诱发持续性室性心律失常、有症状病人出现非持续性室性心动过速、患儿出现低血医相关心肌缺血、出现β肌浆球蛋白重链突变伴猝死家族史以及左心室射血分数不佳。
5) Risk stratification should be done on an individualized basis.
危险度分层分析应根据个人具体情况而行。
6) In those patients in whom a high risk for sudden arrhythmic death is suspected, the only current effective treatment is the implantable defibrillator.
对于心律失常性猝死高危患者，当前唯一有效治疗是植入去颤器。
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