L.C., a 52-year-old female research chemist, has had a history of T-cell lymphoma for 8 years. She was initially treated with systemic chemotherapy with methotrexate until she contracted stomatitis. Continued therapy with topical chemotherapeutic agents brought some measurable improvement. She also had a history of hidradenitis.

A recent physical examination showed diffuse erythroderma with scaling and hyperkeratosis, plus alopecia. She had painful leukoplakia and ulcerations of the mouth and tongue. L.C. was hospitalized and given two courses of topical chemotherapy. She was referred to Dental Medicine for treatment of the oral lesions and discharged in stable condition with an appointment for follow-up in 4 weeks. Her discharge medications included hydrocortisone ointment 2% to affected lesions q hs, Keralyt gel bid for the hyperkeratosis, and Dyclone and Benadryl for her mouth ulcers pm.

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