The symptoms of malignant disease may be related to the size and location of the tumour. For example, a space-occupying lesion in the brain causes raised intracranial pressure and symptoms such as headache, vomiting, or visual disturbance. Tumours of the colon may obstruct (block) the lumen and cause change in bowel habit. Other possible symptoms of malignancy include bleeding, pain,and weight loss.

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